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The combination of these findings positioned NNMT as a candidate metabolic-disease and metabolic-aging research target, motivating development of selective small-molecule inhibitors including 5-Amino-1MQ
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For example: Older adults might need more frequent or higher doses because their bodies absorb less and they are more likely to be deficient
pernicious anemia refers to one of the hematologic manifestations of chronic auto-immune gastritis, in which the immune system targets the parietal cells of the stomach or intrinsic factor itself, leading to decreased absorption of vitamin B 12
Injections can be weekly while refills are made on follow-ups.
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